When you make it to Hannibal, be sure you leave enough time in your day to take a cave tour and take a sightseeing riverboat tour.
If you get hungry, you'll want to stop at Fat Boys and eat a giant tenderloin sandwich while visiting. Take your time to see the sights along the way, there are several lodging and hotel options in Hannibal if you decide to stay the night.
Be sure to stop in at Gateway Harley-Davidson and tell us about your ride!